The investigation on the effect of high velocity low amplitude thrust of the cervical spine to stress response through salivary cortisol

Item

Title
The investigation on the effect of high velocity low amplitude thrust of the cervical spine to stress response through salivary cortisol
Author(s)
Rojoa, Aslam
Abstract
Introduction and ObjectivePain and discomfort are the main reason for which individuals seek osteopathic spinal manipulative treatments. High velocity low amplitude thrust (HVLAT) is one of the many techniques used by an osteopath. There is a growing body of evidence for the efficacy of HVLAT in pain modulation, but the mechanism responsible for the therapeutic effect is unclear. This study investigated whether HVLAT interfered with inflammation through the HPA axis via the inhibition of secretion of cortisol on stressor-induced subjects.MethodsNine healthy subjects, five male and four female subjects (mean age = 26 years, SD = 5) were recruited from the British College of Osteopathic Medicine to participate in the cross over study. The subjects were assigned to three different groups. Capsaicin cream (was used as a stressor and applied to left C5 dermatome and quantification of pain was recorded with a visual analogue scale. The intervention was performed at 20 minutes on the subjects in Group one and two,whereas Group three was the sham group. Salivary cortisol was collected using the IPRO oral fluid collector at 15 minutes (pre intervention) and 30 minutes (post intervention). The salivary cortisol was analysed through an enzyme-linked immunosorbent assay.
ResultsA two-way repeated measures ANOVA was used to evaluate the results with P value set to 0.05. The stressor was successfully induced in all participants with the desired results of pain and inflammation. There was no statistical significant difference in cortisol levels between the groups (p=0.067). Pain perception measured with VAS and no statistical significant difference (p=0.057) was observed.ConclusionThe results of this study suggest that high velocity low amplitude thrust of the cervical spine does not interfere with the HPA axis, supported by other studies with similar findings.
Date Accepted
2018
Date Submitted
9.11.2018 12:15:37
Type
osteo_thesis
Language
English
Number of pages
29
Submitted by:
4457
Pub-Identifier
16211
Inst-Identifier
1076
Keywords
HVLAT, capsaicin, cortisol, HPA axis, manipulation
Recommended
1
Item sets
Thesis

Rojoa, Aslam, “The investigation on the effect of high velocity low amplitude thrust of the cervical spine to stress response through salivary cortisol”, Osteopathic Research Web, accessed May 4, 2024, https://www.osteopathicresearch.com/s/orw/item/2140