The reliability and effectiveness of FeNO in the diagnosis and identification of asthma and exercise-induced bronchoconstriction: A structured Literature Review.
Item
- Title
- The reliability and effectiveness of FeNO in the diagnosis and identification of asthma and exercise-induced bronchoconstriction: A structured Literature Review.
- Author(s)
- Berrett, G
- Abstract
- Background: Exercise-induced bronchoconstriction (EIB) and asthma are conditions that are regularly examined in children, adults and athletes. With increasing numbers of people both taking part in physical activity and showing asthma signs and symptoms, it is questioned which method of examination is most accurate in the diagnosis of EIB/EIA and asthma. FeNO is the more commonly used, due to its suggested quality and accuracy compared with other traditional methods. Objective: To review recent publications that explore the diagnostic accuracy of FeNO in patients suffering or presenting with signs and symptoms of EIB/asthma and evaluate whether FeNO can be accepted as the primary technique in the diagnosis and management. Design: A structured literature review. Methods: A systematic search was carried out to identify studies relevant to the topic in question. The inclusion and exclusion criteria were applied. The remaining studies were then individually assessed using the Downs and Black checklist and the levels of evidence from the Centre of Evidence-based Medicine. These studies were also evaluated and discussed. Results: Nine studies were selected for review following application of the inclusion and exclusion criteria. These present outcomes on the quality and effectiveness of FeNO that support it as a reliable method for diagnosis and management. Following the Downs and Black checklist it was found that only 5 of the studies were considered fair in quality, with the others being poor. 8 of the 9 results obtained across the studies demonstrate that FeNO was effective and reliable. Discussion: With the quality of the studies being low and when considering the wide variety of study types that met the inclusion and exclusion criteria, the reliability and validity of the data gathered must be regarded as questionable. Conclusion: There is insufficient evidence of high quality to prove that FeNO is the definitive method of examining for and diagnosing EIB and asthma. More research is required to gauge the accuracy and quality of FeNO.
- presented at
- European School of Osteopathy
- Date Accepted
- 2019
- Date Submitted
- 19.11.2019 18:31:00
- Type
- osteo_thesis
- Language
- English
- Submitted by:
- 62
- Pub-Identifier
- 16486
- Inst-Identifier
- 1229
- Keywords
- Exercise-induced bronchoconstriction, Exercise-induced asthma, Asthma, Fractional exhaled nitric oxide, spirometry, peak flow, diagnosis.
- Recommended
- 0
- Item sets
- Thesis
Berrett, G, “The reliability and effectiveness of FeNO in the diagnosis and identification of asthma and exercise-induced bronchoconstriction: A structured Literature Review.”, Osteopathic Research Web, accessed May 7, 2025, https://www.osteopathicresearch.com/s/orw/item/343