The effects of sub-occipital inhibition on vessel diameter & peak systolic velocity in healthy subjects measured by 2D & Doppler ultrasound of the right carotid artery.

Item

Title
The effects of sub-occipital inhibition on vessel diameter & peak systolic velocity in healthy subjects measured by 2D & Doppler ultrasound of the right carotid artery.
Author(s)
Joergensen,L
Abstract
Title The effects of sub-occipital inhibition on vessel diameter & peak systolic velocity in healthy subjects measured by 2D & Doppler ultrasound of the right carotid artery. Introduction Hypertension is one of the leading causes of premature mobidity and mortality in the UK. It is a precursor for cerebrovascular events, ischemic heart disease and peripheral vascular disease. Sub-occipital inhibition is thought to stimulate parasympathetic activity to the heart via the vagus nerve and amongst reduce heart rate. Method The study is a repeated measures design experiment using independent groups: a treatment group receiving sub-occipital inhibition (SI) and a control group. Sample size of 32 in total. Initially a 10 min period of rest before the first scan. The images were done in triplicate. Followed by intervention or rest for 5 min. Then the second scan was done, followed by another 5 min rest for both groups. Finally, the third scan was done. The images were obtained by 2D ultrasound scan for vessel diameter and Duplex Doppler scan for peak systolic velocity. Results In Tracker the images were applied measuring rods, which produces the values for the raw data. As the images were in triplicate an average was calculated, which featured as the raw data for further analysis. The following statistical tests were use: F-test, Shapiro-Wilks, T-test and Mann-Whitney. Both within-group comparisons as well as between group comparisons were used. Furthermore, the differences between groups were subjected to rezeroing. The result showed a significant difference in both the intervention and control groups for diameter change from baseline to 5 min post intervention. There was no significant difference between baseline and 5 min post intervention for the peak systolic velocity, and the baseline and directly post intervention for either of the groups. There was no significant difference between the group differences for diameter or peak systolic velocity. Rezeroing showed no statistical significance either, however, the mean rank suggested a larger effect of sub-occipital inhibition for both peak systolic velocity groups and for diameter directly post intervention. The mean rank was larger for the control group 5 min post intervention for the diameter data. Discussion The findings suggest that both sub-occipital inhibition and resting on a couch for 30 min have an effect on vessel diameter 5 min post intervention. There was no statistical significance effect of sub-occipital inhibition on vessels diameter immediately after intervention, and no effect in the control group. The findings showed no statistical significant effect on peak systolic velocity neither immediately nor 5 min after intervention for both groups. The study was limited in sample size and the subjects were normotensive. The complexity of the ultrasound as the measuring modality proved difficult and it is recommended that future studies weight training in the scanning technique. With a better practical understanding and experience of the ultrasound system scans such as blood flow calculations could be done, which would provide a more extensive impression of the hemodynamic in the vessel. Conclusion The study failed to demonstrate an effect of sub-occipital inhibition on peak systolic velocity both immediately and long term. There was also no effect on the vessel diameter immediately after the intervention. However, the results suggest an effect on vessel diameter long term for both the intervention group and the control group with a larger effect of the latter. The study did not generate substantial evidence to support the theory of sub-occipital inhibition as a technique to affect the hemodynamic in blood vessels. This renders the applicability of SI as treatment of hypertension questionable.
Date Accepted
2014
Date Submitted
20.1.2015 16:43:40
Type
osteo_thesis
Language
English
Submitted by:
62
Pub-Identifier
15501
Inst-Identifier
1229
Keywords
Inhibition, Doppler, Vessel diameter.
Recommended
0
Item sets
Thesis

Joergensen,L, “The effects of sub-occipital inhibition on vessel diameter & peak systolic velocity in healthy subjects measured by 2D & Doppler ultrasound of the right carotid artery.”, Osteopathic Research Web, accessed May 17, 2024, https://www.osteopathicresearch.com/s/orw/item/663