Effectiveness of non-pharmaceutical therapies for symptoms relief of Irritable Bowel Syndrome (IBS)

Item

Title
Effectiveness of non-pharmaceutical therapies for symptoms relief of Irritable Bowel Syndrome (IBS)
Author(s)
Tomas, O
Abstract
Background: Irritable Bowel Syndrome (IBS) is a widespread and complex disorder that affects 10-20% of the worldwide population. The syndrome impacts the quality of life of those who suffer from the disorder and is a cost to society. The aetiology of the disorder is still poorly understood and the few treatments available aim to reduce the common symptoms (diarrhoea, constipation, bloating amongst others). Forty-five percent of patients suffering with IBS are not entirely satisfied with conventional treatment and seek help in non-pharmaceutical therapies. Literature reviews comparing different non-pharmaceutical therapies are limited, and this gap in the literature needs to be filled to orientate patients towards the most suitable treatments. Objectives: The objective of this study is to critically appraise the relevant literature of randomised control trials (RCTs) published within the last 10 years, and to determine whether non-pharmaceutical therapies can relieve and/or prevent symptoms associated with IBS. Design: Structured literature review from randomised control trials published between January 2009 - August 2019. Methods: A systematic search of relevant literature was conducted in September 2019. To identify eligible studies, the search was conducted using the following databases: Cochrane Library, MEDLINE-PUBMED, Science Direct and Google Scholar. Boolean logic was used, and filters were applied to fit the inclusion and exclusion criteria. The quality of included trials was assessed with JADAD and PEDro scales, and these scales respectively rate quality of evidence from “low” to “high”, indicating validity and reliability of articles. Studies were summarised and compared against the evidence of previous findings. Results: 2796 records were found; only 12 studies were included in the review after selection and filtering. A total of 4 treatment modalities were studied. Eleven of the studies were assessed as being of fair to high quality according to the PEDro score. Although there was heterogeneity in the outcome measures and control interventions. All studies reported more better short-term improvements with the modality tested compared with sham therapy, standard care only or another therapy. Discussion: The limited number of high quality RCT assessed, associated to heterogeneity in outcomes measure in between studies makes it difficult to draw definite conclusion.Conclusion: Preliminary evidence is shown regarding the effectiveness of non-pharmaceutical therapies in reducing IBS symptoms. However, a meta-analysis helping to determine which of the therapies is the most effective could benefit patients and practitioners.
Date Accepted
2020
Date Submitted
28.10.2020 18:08:19
Type
osteo_thesis
Language
English
Submitted by:
62
Pub-Identifier
16697
Inst-Identifier
1229
Keywords
Complementary medicine, non-pharmaceutical therapies, IBS, symptoms management.
Recommended
0
Item sets
Thesis

Tomas, O, “Effectiveness of non-pharmaceutical therapies for symptoms relief of Irritable Bowel Syndrome (IBS)”, Osteopathic Research Web, accessed May 2, 2024, https://www.osteopathicresearch.com/s/orw/item/906